Dr. Keigo Gohda

Birth: Himeji, Hyogo, Japan in 1963                                       

EDUCATION

April 1982 - March 1986

         Faculty of Pharmaceutical Sciences, Osaka University
         Majoring in Nucleotide Chemistry with Prof. Dr. M. Ikehara
         B. S. received March 1986
         Title: Synthesis of 2'-substituted nucleosides

April 1986 - March 1988

         Graduate School of Pharmaceutical Sciences, Osaka University
         Majoring in Biochemistry with Prof. Dr. S. Uesugi, coreferent Prof. Dr. T. Hakoshima 
         M. S. received March 1988
         Title: Effects of 2'-substituents of deoxynucleoside residues in DNA/RNA on the 

                 activity of nucleases

December 1997

         Ph. D. in Biochemistry from Graduate School of Sciences, Osaka University
         Majoring in Biochemistry with Prof. Dr. Y. Kyogoku
         Title: Structural studies on the reaction mechanism and substrate binding 

                 manner of ribonuclease T1

EMPLOYMENT

April 1988 to March 1997

          International Research Laboratories, CIBA-GEIGY Japan Limited

          as a Computational Chemist

April 1994 - July 1995

          R&D Division, CIBA-GEIGY Basle AG, Switzerland

          as a Computational Chemist

April 1997 to December 1999

          Takarazuka Research Institute, Novartis Pharma K. K.
          as a Computational Chemist (Lab. Head)

January 2000 - February 2001

          Tsukuba Research Institute, Novartis Pharma K. K.
          as a Computational Chemist (Lab. Head)

March 2001 to present

          A foreign pharmaceutical company 

          as a Clinical Research Staff

OFFICIAL LICENSES, QUALIFICATIONS or PRIZES/AWARDS

October 1986

          License of Pharmacist

October 1997

          Poster Award in the 25th Structure-Activity Relationship Symposium

          organized by the Chemical Society of Japan

TECHNICAL BACKGROUND

Molecular Modeling
   Structure-based Drug Design
   3D-database Search
   de novo Design
   Protein Modeling
   3D-QSAR
   Classical QSAR
   MO Calculation

Software
   QUANTA / CHARMm
   SYBYL / CoMFA / Leapfrog
   MacroModel / Maestro / BatchMin
   CERIUS2
   DISCOVER / INSIGHT
   AutoDock
   DOCK

   AMBER
   Gaussian94
   Spartan
   MOPAC

   CSD / Cambridge Crystal Database
   MACSS-II
   ISIS

Languages / Systems
   UNIX
   VMS / DEC
   FORTRAN
   C
   SPL / SYBYL
   CHARMm
   X-PLOR

   Windows 95/NT
   IBM-PC
   Mac

   Network / TCP-IT
   Internet / Web tools